PSpice by Cadence Design Systems, Inc is a native analog and mixed-signal circuit simulator. Sadly, PSpice for Mac is not yet available. Anyway, if you were looking for PSpice for Mac, you can try these applications, as these circuit simulators are also quite handy and have similar functions and features.
Feel free to add any alternative to PSpice for Mac that you know of.
Suggest Alternatives
Can I use this tools to combine smaller circuits into larger ones?